AlphaFold An artificial intelligence system developed by Google DeepMind that predicts three-dimensional protein structures from amino acid sequences and, in AlphaFold 3, models biomolecular complexes ...

Proteins are the molecular workhorses of cells. To understand their functions, scientists soon realized that they had to figure out proteins’ shapes. But solving a protein structure is a challenging ...

Artificial intelligence (AI) is reshaping the scientific landscape, offering fantastic solutions to some of the most pressing global challenges. From combating climate change to transforming ...

The artificial intelligence–based structure-prediction software AlphaFold, originally developed by Google DeepMind, has quickly become an important tool for drug discovery. Its original iteration ...

The AI-based program AlphaFold predicts a protein's 3D structure with remarkable accuracy. However, it tends to reduce heterogeneous structures to a single dominant conformation, or shape, and ...

“I’ll be shocked if we don’t see more and more LLM impact on science,” says John Jumper. In 2017, fresh off a PhD on theoretical chemistry, John Jumper heard rumors that Google DeepMind had moved on ...

Kent Hall buzzed with anticipation as a standing-room-only crowd of University of Chicago scientists and students eagerly awaited a talk by UChicago alum John Jumper, who won the 2024 Nobel Prize in ...

The intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making structure prediction particularly challenging. These ...

Google DeepMind’s work with AlphaFold has been nothing short of a miracle, but it is computationally expensive. With that in mind, Apple researchers set off to develop an alternative method to use AI ...