Alveolar fibroblasts play a key role in regulation of lung inflammation. Pseudomonas aeruginosa (PAO) is one of the most common pathogens causing lung injury, and the role of PAO-infected alveolar ...
“Novel senomorphic and senolytic agents can be evaluated in this model as they are identified.” Idiopathic pulmonary fibrosis (IPF) is an age-related disease with poor prognosis and limited ...
Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic fibroblasts without using stem cell technology. The AT2-like cells ...
Japanese researchers have generated lung cells directly from mouse tissue. These lung cells are called Alveolar Epithelial Type 2 (AT2 cells). A team led by Professor Makoto Ishii from Nagoya ...
Researchers from Columbia University Irving Medical Center and collaborators applied unbiased scRNA-seq to study Lepr expression in lung mesenchymal cells. To do that, they used a Lepr(creERT2) mouse ...