A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid without ...
In proteins, amino acids are held together by amide bonds. These bonds are long-lived and are robust against changes in temperature, acidity, or alkalinity. Certain medicines make use of reactions ...
Linking molecular components through amide bonds is one of the most important reactions in research and the chemical industry. Scientists have now introduced a new type of reaction for making amide ...
Alpha-substituted fatty amines and nitrogen-containing heterocycles are widely found in numerous bioactive natural products, pharmaceutical molecules, and agrochemicals. A recent analysis of small ...
Nature typically outdoes chemists when it comes to efficiently carrying out reactions. But for a nickel—or make that a simple nickel catalyst—a team of UCLA chemists has matched wits with enzymes on ...
Two new skeletal editing techniques offer a way to create an array of nitrogen-containing rings. Nitrogen heterocycles are ...
Even though amide bonds are everywhere—they hold proteins together and are essential components in many drugs—forging this molecular motif in a reaction flask can be challenging. For example, making ...
A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...
In proteins, amino acids are held together by amide bonds. These bonds are long-lived and are robust against changes in temperature, acidity or alkalinity. Certain medicines make use of reactions ...
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