Although numerous platforms have been developed to support array CGH studies, they all revolve around a common principle of detecting copy number alterations between two samples (Figure 1). These ...
Mantle cell lymphoma (MCL) is characterized by t(11;14)(q13;q32), which results in overexpression of CCND1, and is presumed to derive from naive pre-germinal center CD5 + B cells (Seto et al., 1992; ...
Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...
Early efforts to examine genomic changes in the clinical setting relied on cytogenetic techniques such as chromosome karyotyping, a widely used approach to examine chromosomes and identify changes ...
Predictors of survival in advanced renal cell carcinoma (RCC): Long-term results from Southwest Oncology Group trial S8949 No significant financial relationships to disclose. This is an ASCO Meeting ...
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