Researchers suggest targeting ECM-mediated regulation of autophagy levels could be used to sensitize pancreatic cancer to FDA-approved therapies.

Autophagy a self-eating process where the body’s cells recycle their own damaged components to maintain health Our experts ...

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows. The ability of these cancer cells to adapt quickly and ...

Researchers found that pancreatic cancer cells sense the extracellular matrix to regulate autophagy, toggling between rapid growth and chemotherapy resistance.

Research from investigators at Rutgers Cancer Institute of New Jersey and the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, shows the intracellular process of ...

Novel autophagy research traces new mammalian pathways and reveals unexpected impact of SARS-CoV-2 infection. The intricate biological process known as autophagy plays a vital role in keeping our ...

The mechanism of astrocytic autophagy plasticity plays a crucial role in AD. When the autophagy-regulating genes (LC3B and SQSTM1) in astrocytes are activated, Aβ is efficiently removed, which is ...

Proteins classically associated with autophagy regulate the speed of intracellular transport. Scientists from the laboratory of Dr. Natalia Kononenko at the CECAD Center of Excellence in Aging ...

Plant‐pathogenic fungi rely on finely tuned cellular processes to invade host tissues and sustain infection. This study ...