While current clinical trials for cardiac regeneration using induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) employ immunosuppressive regimens used in heart transplants, the precise ...

Researchers from Leiden University Medical Center (LUMC) and the Leiden-based biotech company Ncardia have joined forces to ...

The endoplasmic reticulum (ER) regulates protein folding and maintains proteostasis in cells- a process essential to maintaining cellular health. However, researchers at UAB have found that chronic ...

The adult mammalian heart bears limited regenerative capacity, resulting in the irreversible loss of cardiomyocytes post-cardiac injury, and often culminating in end-stage heart failure. Cardiomyocyte ...

When a patient is experiencing heart failure, a leading cause of death worldwide, they begin to lose healthy and functioning cardiac cells. Heart failure causes these once-flexible cells to develop ...

Regenerative heart therapy, integrating biocompatible materials with nucleic acids, proteins and live cells, offers a promising personalized approach to treating cardiac ischemic reperfusion injury ...

Please provide your email address to receive an email when new articles are posted on . Aficamten was linked to improved exercise capacity and quality of life for patients with obstructive HCM. The ...