For the first time, a stem cell model has produced a structure resembling an early human embryo with a yolk-sac-like structure, from a single starting stem cell population and without direct genetic ...

Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...

“Hey model, if I prompt you with the marker genes for a cell type, can you complete the transcription factors that you believe would be highly expressed with expression of these genes?” posed ...

Biomedical research typically follows a familiar path: developing treatments that block, enhance or mutate certain signaling pathways, genes or proteins to change the function of different cells in ...

Biomolecular condensates were long believed to be simple liquid blobs inside cells. Researchers have now uncovered that some are actually supported by fine protein filaments forming an internal ...

Scientists at Feinberg are reshaping scientific understanding of the cell's tiniest components—structures once thought to be static, now revealed to be dynamic engines of cellular life. As they probe ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...