Hepatocellular carcinoma (HCC), the most common primary liver cancer, poses a global health threat with over 680,000 new diagnoses and 620,000 deaths annually. Current immunotherapies often fail due ...

As people age, chronic inflammation can ensue. What drives this so-called “inflammaging”? A study published August 2 in Nature may have identified a primary cause, at least in the mouse brain.

Cyclic GMP-AMP synthase (cGAS) functions as a foreign DNA sensor, triggering an immune response to pathogens by activating the STING (stimulator of interferon genes) receptor. Shortly after its ...

Novartis is stepping on the cGAS. Three years after securing an option on an IFM Therapeutics subsidiary, the Swiss drugmaker has accelerated into the deal and paid $90 million upfront for small ...

WALTHAM, Mass. & MONTREAL--(BUSINESS WIRE)--Ventus Therapeutics, a clinical-stage biopharmaceutical company advancing two Phase 2 small-molecule programs for immunological, inflammatory, and ...