Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...
DNA inside human cells is not just floating around freely. It is tightly wrapped around small proteins, forming a long chain.
New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their failures may drive disease.
There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...
High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact within these droplet-like structures. The findings connect molecular ...
A game-changining achievement in genome science has identified over 140,000 distinct DNA loops in our cells, providing chromosome fold resolution that is among the best ever created. In this ongoing ...
Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...
Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...
Chromatin is a unique DNA and protein complex that makes up the chromosomes. Specific proteins (histones) wind up the DNA like small cable drums to package the long DNA. A cable drum (consisting of ...
Myelodysplastic syndrome (MDS) arises from defective blood stem cells that progressively lose their normal functions.