Liddle syndrome is an autosomal dominant disorder caused by hyperactivity of the amiloride-sensitive sodium channel (ENaC) of the principal cell of the cortical collecting tubule. In 1963, Liddle ...
Precise control of sodium excretion by the kidney is critical for maintaining fluid and electrolyte homeostasis. A new mouse model provides compelling evidence that a kinase, WNK4, provides key ...
Bethesda, Md. (Sept. 22, 2011) – The kidney performs several vital functions. It filters blood, removes waste products from the body, balances the body's fluids, and releases hormones that regulate ...
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