Thermal Gradient Gas Chromatography (TGGC) employs dynamic temperature profiles along the chromatographic column to enhance separation efficiency and peak resolution. This technique, when integrated ...

Gradient elution involves a programmed change in mobile-phase composition over time, transitioning from weak to strong during a separation. Linear gradients, characterized by a constant change in ...

Operating HPLC at higher than ambient temperatures can improve peak shapes and enable faster run times. Preheating the mobile phase is significant in high temperature liquid chromatography as the ...

One of the most common themes associated with all omics applications is the ever-increasing size of patient cohorts. This increase is prompted by the need to identify novel disease biomarkers and an ...

Liquid chromatography (LC) is an essential technique is many analytical labs. Whilst a fully-tuned chromatography workflow can be an invaluable tool, the technique comes with a lengthy development ...

Case in point: For more than a century, chromatography practitioners have been separating the components of chemical mixtures by using columns packed with various types of particulate matter. Recently ...

Although biopharmaceutical manufacturing covers an extensive range, it is essential that each iteration of a unit operation is in compliance with an unyielding set of operational parameters and ...

Downstream bioprocessing steps have long been a challenge to drug manufacturers, particularly the chromatography step for purification of monoclonal antibodies (mAbs). The complexity of traditional ...

Advanced analytics and modeling can be used to predict downstream failures, allowing for corrective action before batches are lost. In the biopharmaceutical industry, quality and consistency are two ...