The ever-expanding field of high-content analysis (HCA) continues to lure scientists from many disciplines. Because of its versatility, high-content screening can be used for many applications ...

Researchers Attempt to Make Sense of Massive Amounts of Data High-content analysis (HCA) is emerging as one of the fastest growing sectors in drug discovery and development. It represents the ...

Fluorescent techniques have largely replaced transmitted light methods in recent decades, allowing users to confidently identify many distinct cellular structures, such as nuclei, mitochondria, ...

Antibody-drug conjugates (ADCs) are transforming oncology by combining the precision of monoclonal antibodies with the potency of cytotoxic drugs. Yet, developing effective ADCs requires overcoming ...

High-Content Analysis (HCA) merges the benefits of high-throughput automation and unbiased analysis with microscopic imaging. This powerful - and now highly accessible - technique allows researchers, ...

No modern laboratory is complete without at least one basic microscope, an essential tool for biologists in medical research. Transmitted light methods have largely been replaced by fluorescent ...

Polyploid circulating stromal cells in blood to identify invasive solid tumors and to prognosticate for highly aggressive cancer subtypes. This is an ASCO Meeting Abstract from the 2024 ASCO Annual ...

Cell models used for HCS range from immortalized cell lines to primary cells, induced pluripotent stem cell (iPSC)-derived systems, and increasingly, three-dimensional cultures. Selection of the ...