For decades, methotrexate has formed the foundation of therapy in RA, either alone or in combination with other drugs; however, its mechanisms of action remain poorly understood, and many patients ...

Researchers studying cultured cells shortly after infecting them with SARS-CoV-2, now have more insight into the metabolic pathways co-opted by the virus. The findings highlight the potential ...

Defining Burkitt’s lymphoma (BL) with cytogenetics: LY10, a prospective clinicopathological study of dose-reduced (dr) CODOX-M/IVAC in patients with 100% Ki-67 staining B-cell non-Hodgkin’s lymphoma ...

Disclosure: The author has no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials ...

The novel beta-coronavirus virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and coronaviruses, in general, alter the host's cellular metabolism to support massive production of ~30 ...

Folinic acid is an active form of folate, while folic acid must be converted in the body. Leucovorin (folinic acid) is prescribed for methotrexate toxicity, megaloblastic anemia, and advanced ...

Methotrexate is one of the oldest and most cost-effective medicines available for rheumatoid arthritis (RA). Its also one of the most commonly used RA therapies. Heres what to know about this drug if ...

Methotrexate is a slow-acting disease-modifying antirheumatic drug (time to maximum therapeutic response is approximately 6 months), and delayed dose escalation might result in a loss of efficacy.

A new study that looked at health data from the UK found people with a folic acid prescription were 1.5 times as likely to get COVID-19 and were more than 2.6 times as likely to die from COVID-19 ...