In the earliest phase of creating human proteins, the protein complex NAC performs an essential task by starting the first steps toward folding proteins into their correct three-dimensional structures ...

Merck researchers developed a highly sustainable way to synthesize the macrocyclic peptide drug enlicitide, increasing ...

Scientists at the University of California, Santa Cruz, have trapped the ribosome, a protein-building molecular machine essential to all life, in a key transitional state that has long eluded ...

Targeted protein degradation is changing how drug discovery teams think about disease biology. For many years, small molecule programs were built around inhibition. A compound was expected to bind a ...

An illustration showing how the nascent polypeptide-associated complex (NAC, green) at the ribosome (blue) helps the amino acid chain (white) to fold into a protein. In the earliest phase of creating ...