Liposomes are vesicles in which an aqueous volume is entirely enclosed by a membrane composed of lipid molecules, usually phospholipid. They can be prepared so that they entrap materials both within ...

Polypeptides that are being discovered by the biotechnology industry hold great promise as new drug candidates to target specific disease symptoms. However, polypeptide drugs are rapidly degraded by ...

The modification of the liposomal surface by incorporating negatively charged lipids (e.g., by dicetylphosphate [DCP] incorporation), seems to increase the AM affinity to capture anionic liposomes via ...

Cationic liposomes are widely used in gene therapy as a safe alternative to highly immunogenic viral vectors. Attachment of a tissue-specific ligand to the surface of the liposomes can increase ...

The surprise in the current study was the rapid and long-lasting effect of one injection of the RGD-liposomal dexamethasone-phosphate formulation, indicating that early therapeutic intervention at the ...