By understanding how milligram to kilogram peptide production is achieved safely, drug developers can better navigate the ...
Aza-peptides, peptide analogues in which one or more α-carbon atoms are replaced by nitrogen atoms, represent a promising class of compounds in therapeutic development. This structural modification ...
The breakthrough could simplify the production of complex proteins used in cancer immunotherapy and other advanced medicines ...
A major problem in solid-phase peptide synthesis (SPPS) is aggregation and poor solvation leading to incomplete deprotection and/or coupling steps, resulting in low crude purity peptides. 1 This ...
A recent video produced by Vapourtec highlights the patented automatic Variable Bed Flow Reactor (VBFR) demonstrating fully automated solid phase peptide synthesis. The process begins with swelling ...
Promising Technology Demonstrates Results in Peptide Synthesis and Proteomic Sample Prep One of the greatest advances in solid phase peptide synthesis (SPPS) and proteomics over the past decade is the ...
Pharmaceutical scientists at the National University of Singapore (NUS) have developed a novel chemical reaction that enables the precise functionalization of peptides and proteins. This approach ...
In a pharmaceutical world so often divided by molecules large or small, peptides have struggled to find their place.
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