Mechanosensitive cation channels have key roles in converting mechanical stimuli into various biological activities, such as touch, hearing and blood pressure regulation, through a process termed ...

Tracing the impact of a single protein, Piezo1, researchers found that restoring it in muscles affected by Duchenne muscular dystrophy could improve their ability to heal efficiently. One protein, ...

The brain is the softest organ of the body, so when rigid Aβ plaques form, they stand in stark contrast to the squishiness surrounding them. Microglia sense this rigidity via Piezo1, a calcium channel ...

The left image shows the trabecular meshwork as it can be seen in a doctor's office. The right image shows a portion of the same part of the eye in much greater detail using methods developed at IU.

The ability to sense mechanical stimuli, like touch or blood pressure, is essential to physiological processes in humans and across the animal kingdom. In a new study, Scripps Research scientists show ...

A study by scientists at Harvard Medical School and the Icahn School of Medicine at Mount Sinai has revealed how a pressure-sensitive protein, PIEZO1, helps regulate intestinal motility and control ...