Post-translational modifications (PTMs) of tubulin, including acetylation, glutamylation and detyrosination, play a critical role in dictating the dynamic behaviour and specialised functions of ...

Post-translational modifications (PTMs) play a key role in dynamic cellular processes, regulating gene expression, protein activity, localization, and degradation, as well as protein interaction.

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

Built on groundbreaking research from Israel ’s Weizmann Institute of Science, Promise Bio developed the first cloud-based platform for broad epiproteomics, helping researchers uncover disease ...

Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and ...

Non-CHO cell expression systems gain traction as faster, more flexible alternatives for biologics manufacturing.

A new study led by Nicolás Bologna, a CSIC researcher at the Center for Research in Agricultural Genomics (CRAG), sheds light on the crucial role of the N-terminal extension (NTE) of AGO proteins, ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

Explore how proteomics enables personalized medicine by improving patient stratification, treatment response, and diagnostics ...

This multidisciplinary project integrates computational biology, structural modelling, population genomics, and AI. It will provide new mechanistic insights into how coding variation and PTMs ...