Chemical cross-linking (XL) is widely used to investigate protein–protein interactions (PPIs), including transient or low abundance subcomplexes in mass spectrometry workflows. However, identifying ...

Proteins have specific biological functions in cells through conformational changes and interactions. Therefore, precise, in situ analysis of protein complex changes is essential for understanding ...

Many diseases are driven by proteins interacting with each other inside cells. But blocking these interactions with drugs is ...

Researchers have developed a type of peptides that can enter cells and block protein interactions considered difficult to ...