Machine-learning platform enables signal peptide-informed discovery of small molecules that selectively inhibit protein secretion allowing for the degradation of disease-related proteins at the point ...
11monon MSN
Scientists create method for designing proteins that can bind and sense a range of small molecules
The subunits, being modular, are easily disassembled. In this way, the small-molecule-binding proteins can be treated like ...
HOUSTON & MILAN--(BUSINESS WIRE)--Sibylla Biotech and The University of Texas MD Anderson Cancer Center today announced a strategic collaboration agreement to discover and develop novel small-molecule ...
Membrane proteins are vital for cellular signaling, transport, and communication, making them attractive drug targets despite their challenging properties. Advances in mass spectrometry have enabled ...
Experts have developed a breakthrough small-molecule drug, a 'protein degrader'. This molecule, called ACBI3, could potentially lead to new therapies independent of KRAS mutation type, improving ...
Drug discovery requires two separate steps: checking whether a drug can bind to a harmful molecule or its receptor, and ...
This review provides an overview of traditional and modern methods for protein structure prediction and their characteristics and introduces the groundbreaking network features of the AlphaFold family ...
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