Genetic disorders — like cystic fibrosis and Huntington’s disease — are considered incurable, with gene mutations occurring in essentially every cell of the body. Gene mutations occur when one ...

New modeling shows how synonymous mutations — those that change the DNA sequence of a gene but not the sequence of the encoded protein — can still impact protein production and function. A team of ...

Synonymous or silent mutations do not change the sequence of the protein that they encode. With some exceptions, they do not trigger any effect. Last year, however, a study by researchers from the ...

Infographic: How “Silent” Mutations Can Disrupt Protein-Making Although scientists often assume that synonymous mutations don’t cause any biological effects because they don’t alter the amino acid ...

A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...