Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic ...

Researchers have identified 813 possible cancer driver genes, significantly expanding the list of potential therapeutic targets for treating the disease. The genes help cancer cells grow through a non ...

Cancers driven by hiccups in RNA processing can’t hide from our immune system, according to new work published today in Cell. A cross-institutional team Fred Hutch Cancer Center and Memorial Sloan ...

Many human diseases are caused by point mutations that affect RNA splicing. It has been observed that nonsense mutations that generate premature termination of translation products can drive the use ...

The protein complex cohesin is fundamental to the cell division process, as it holds sister chromatids tightly together in a ringlike structure before a cell physically splits. But now researchers at ...

Spliceman is not a superhero, but it does have the power to accomplish superhuman feats. Developed by a team of University researchers, the web-based application to identify mutations in gene ...

Scientists have discovered a mechanism that linked a leukemic mutation to varying potentials for disease development -- a discovery which could eventually lead to a way to identify patients with the ...