Enhancers, which are thought to turn genes on by coming into physical contact with gene promoter regions through transiently forming a complex, were discovered about 45 years ago. More recently, in ...
Organisms are made up of cells, and in each of those cells, a genome encodes the instructions for that organism to grow and survive. The human genome has at least 20,000 genes, and the expression of ...
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Gene regulation study reports surprising results: Extensive regions of DNA belong to multiple gene switches
Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA. Different enhancers are ...
Genetic studies of diseases map segments of the genome driving disease. But to understand how those changes contribute to disease progression, it is important to understand how they may alter gene ...
The human genome contains about 23,000 genes, but only a fraction of those genes are turned on inside a cell at any given time. The complex network of regulatory elements that controls gene expression ...
Genome-wide association studies (GWASs) have linked genetic variants to neuropsychiatric disorders, but their regulatory roles in non-coding regions remain largely unclear. Using the LUHMES neuronal ...
In a study published in Genome Research, a team of researchers, including Cornell College Assistant Professor of Biology Sophie Gillett, looked at regions of human genetic code that are known for ...
The human genome contains about 23,000 genes, but only a fraction of those genes are turned on inside a cell at any given time. The complex network of regulatory elements that controls gene expression ...
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