Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers like leukemia and ...

A new CAR T-cell therapy attacks supportive cells in the tumor microenvironment that bear the surface protein, uPAR.

Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals must be ...

A technique that transforms immune cells into cancer-seeking bloodhounds may overcome a roadblock that has hampered ...

Researchers at the Keck School of Medicine of University of Southern California (USC) have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response ...

For the 80 million people worldwide with celiac disease, the only treatment available is to cut grains like pasta and bread out of their lives. But researchers are hoping to change that with a new ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before. This breakthrough may help explain why immunotherapy works for some ...

The University of Georgia has been at the forefront of research utilizing transgenic mice. These genetically modified mice are valuable in studying human diseases due to their genetic similarity to ...