Discover how therapeutic peptides act as biological messengers to treat disease, improve metabolism, and enhance immune ...

Chemical synthesis and peptide ligation techniques have revolutionised the field of protein engineering by enabling the precise construction of peptides and proteins with tailored modifications. These ...

What is it? As the name suggests, nonribosomal peptide synthesis (NRPS) generates polypeptides sans ribosome. The resultant peptides, generally short oligomers of two to perhaps 48 residues, are not ...

A peptide sequence that performs well at micromole scale may behave unpredictably at gram or kilogram scale. Coupling efficiency, acceptable with high reagent excess, can drop when equivalents are ...

Synthetic peptides, generally less than 20 amino acids in length, are essential reagents for a wide range of studies and one of the fundamental tools of proteomics researchers. Applications include ...

A major problem in solid-phase peptide synthesis (SPPS) is aggregation and poor solvation leading to incomplete deprotection and/or coupling steps, resulting in low crude purity peptides. 1 This ...

"Many existing methods either involve many time-consuming steps, only work for a narrow set of molecules, or require further manipulations before ready for peptide synthesis," Kohnke said. The new ...

The Peptide-Builder is designed for peptide chemists who want to make high-quality peptides quickly and easily at a laboratory scale. Peptides are synthesized sequentially and fully automated either ...

The Peptide-ExplorerLT ™ is designed for scientists who need to optimize and explore linear peptide synthesis. The product is a high-spec flow chemistry system that uses continuous flow. The product ...