A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to ...

Animal studies often fail to predict human tissue responses to new drugs or newly developed therapies. Besides generating ...

Researchers have developed a groundbreaking cell culture platform that enables the formation of two distinct but interconnected vascular networks. Their breakthrough holds tremendous promise for ...

Bioprinting holds the promise of engineering organs on demand. Now, researchers have solved one of the major bottlenecks—how to create the fine networks of blood vessels needed to keep organs alive.

Angiography is a widely used medical imaging technique that allows medical researchers and doctors to capture the vascular network (i.e., blood vessels) using contrast agents, substances that enhance ...

The costliness of drug development and the limitations of studying physiological processes in the lab are two separate scientific issues that may share the same solution. Microphysical systems (MPSs) ...

Researchers at Niigata University have used advanced three-dimensional (3D) imaging to reveal how amyloid β (Aβ) deposits spread along blood vessels in the human brain in cerebral amyloid angiopathy ...

Using postmortem human brain tissue, three-dimensional imaging revealed vascular Aβ deposition patterns and a lower density of parenchymal amyloid plaques surrounding Aβ-positive vessels. Smooth ...