Leptin modulates the negative inotropic effect of interleukin-1β in cardiac myocytes, Molecular and Cellular Biochemistry | DeepDyve
deepdyve.com
Leptin modulates the negative inotropic effect of interleukin-1β in cardiac myocytes, Molecular and Cellular Biochemistry | DeepDyve
Interleukin-1β (IL-1β) is a potent negative inotrope implicated in the functional abnormalities of heart failure. Because the adipokine, leptin, protects against some of the cardiovascular effects of endotoxin, we hypothesized that leptin may modulate the cardiosuppressive effects of IL-1β in isolated cardiomyocytes. Ventricular cardiac ...
Jun 6, 2008
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