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Primary Cancers Known to Metastasize to the Liver Categorized by Origin — Gastrointestinal vs. Extra-Gastrointestinal In my exam, there was a question asking: “Which cancer does not metastasize to the liver? Prostate cancer can metastasize to the liver — but it is uncommon.It’s not the usual or early site of spread. Most common sites for Prostate cancer Metastasis is Bone (osteoblastic) ,Lymph nodes and Lungs Liver involvement Occurs late, typically in advanced or castration-resistant prostate c
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🧬 Can prostate cancer be switched off? Here’s what researchers have just discovered about castration-resistant prostate cancer (CRPC) the advanced form that keeps growing even when testosterone is eliminated. It turns out one crucial tumor suppressor gene PTEN is often shut down in these aggressive cases. And the “switch”? A lesser-known molecule called KDM3B. ✅ When KDM3B is high → PTEN stays ON → Cancer slows down. ❌ When KDM3B is low → PTEN turns OFF → Cancer accelerates. Most CRPC patients
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