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Pyruvate Dehydrogenase
Complex
LDH
Isoenzymes
Isocitrate
Pyruvate
Decarboxylation
Pyruvate
Metabolism
Synthesis of Ethyl
Pyruvate
Pyruvate
Oxidation
Lactate
Dehydrogenase
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to acetyl-CoA Pathway
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Pyruvate
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Lactate Dehydrogenase
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Pyruvate
7:57
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Oxidative Decarboxylation of Pyruvate | Pyruvate dehydrogenase complex | #neet # netjrf #biochem
Oxidative decarboxylation of pyruvate is a link reaction between glycolysis and the Krebs cycle. In the mitochondrial matrix, pyruvate (3-carbon) loses one carbon as CO₂, gets oxidized, and forms acetyl-CoA. During this process, NAD⁺ is reduced to NADH. The reaction is catalyzed by the pyruvate dehydrogenase complex and is irreversible.
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